HUKUM ISLAM DAN MASALAHNYA DI INDONESIA

Hukum Islam dan Masalahnya di Indonesi

KNOWLEDGE, ATTITUDES, AND PRACTICES TOWARD CORONAVIRUS DISEASE-19 INFECTION AMONG RESIDENTS OF DELHI NCR, INDIA: A CROSS-SECTIONAL SURVEY BASED STUDY

Objective: In the given study, we have carried out a survey among general population of Delhi NCR (India) for the knowledge, perceptions, and attitude toward coronavirus disease (COVID-19) and also attempted to reach to a few conclusions in the form of recommendations. Methods: A cross-sectional questionnaire based online survey (using Google Forms) was conducted between April 2020 and May 2020 to investigative knowledge, perceptions, and attitude toward COVID-19. Chi-square test was used for the computation of p-value. Results: There were total 823 respondents, with 43.01% females and 56.98% males. Around 73.74% respondents believe that it has become a social stigma. About 75.09% were of the opinion that sneezing etiquettes can help in curbing the infection. About 93.43% of study population follows the personal hygiene, 24.78% wished to get insurance coverage. Similarly, interesting data were collected over different aspects of COVID-19. Conclusions: The current pandemic is the first exposure at such a large scale to the existing population but with the progression of time, authorities and general population are collating knowledge about the same. It is to be fought at all the fronts such as medical, social, economic, and psychological. Hence, this type of survey becomes an important tool in decision making

DRUG UTILIZATION EVALUATION OF ANGIOTENSIN RECEPTOR BLOCKER (ARB) ALONG WITH THEIR ADRS IN A TERTIARY CARE HOSPITAL

Objective: To evaluate the drug utilization of Angiotensin Receptor Blocker (ARB) along with their ADRs in a tertiary care hospital. And to monitor, report of adverse drug reaction and drug interactions, if any. Methods: The patients who meet the inclusion and exclusion criteria were enrolled into the study. The pertinent data such as demographic details, drug name, dose, frequency, and laboratory data were gathered from medical records of the patient and results were analyzed. Results: Total of 100 patients were included in this study, the maximum utilization of antihypertensive drug (ARB) was telmisartan (90%) and widely use of ARBs in the age group of 41-50 y. Total 32 ADRs were observed and most probable ADRs included headache (42.8%), Nausea (14.28%) and dizziness (12.5%). Conclusion: Telmisartan was the most prescribed and utilized drug than the other drugs of ARBs. Maximum ADRs were noted in females, the most frequent ADRs headache, nausea and dizziness were reported. The majority of reactions were probable on causality assessment done by WHO-UMC and Naranjo’s scale having mild severity. So it can be concluded that considering risk factors, prevention and management of ADRs can drastically improve the therapeutic outcomes of the patients

DRUG UTILIZATION BASED ADRs DETECTION OF ANTIBIOTICS PRESCRIBED FOR LRTI IN TERTIARY CARE TEACHING HOSPITAL, NEW DELHI

Objective: Aim of to present study was to assess drug utilization pattern of antibiotics use in Lower respiratory tract infection and their adverse drug reaction assessment.Methods: The present study was an observational and prospective study. 110 patients fulfill the inclusion criteria were included in study. Physician prescription records, patient's medication profile types of antibiotics prescribed were recorded and analyzed.Results: Out of 110 LRTI patients, 74 (67.27%) patients were male and 36(32.72%) patients were female. 72 patients were suffered from bronchitis while 38 patients were suffering from pneumonia. 30 patients were in the age range of 56-65 y, followed by 21 patients who were in the age range of 66-75 y. It has been observed that among all the prescribed antibiotic agent's frequency of β-lactam 199(45.53%), quinolones115 (26.27%), macrolides 53(12.12%) chloramphenicol44 (10.06%) sulphonamide 17 (3.89%) and aminoglycosides 9(2.05%) were prescribed to all the patients. Average 3.97 antibiotic agents were prescribed to all the patients. Majority of drugs were given by oral route (68.19%) and Prescriptions are mainly ordered in brand names. The most frequent co-morbid condition was found to be diabetes mellitus (25.45%) followed by hypertension (16.36%) and coronary artery disease (11.81%).45.45%. Only 23 ADRs were detected in 110 patients. The most common culprit was an amoxicillin with clavulanic acid.Conclusion: The present study provides an overall pattern of antibiotic usage in different patients. The area of concern in the present study is polypharmacy and use of antibiotics in LRTI without following any guideline. ADRs monitoring is also required to prevent noxious effects of drugs by the use of antibiotics

EVALUATION OF AQUEOUS FRUIT EXTRACT OF TAMARINDUS INDICA (L) FOR INHIBITION OF TUMOR NECROSIS FACTOR-a AND CYCLO OXYGENASE ENZYMES IN EXPERIMENTAL ANIMAL

 Objective: The main objective of this study was to assess tumor necrosis factor-α (TNF)-α and cyclooxygenase enzymes (COX) inhibition potency of Tamarindus indica Linn. in comparison to standard drug (indomethacin).Methods: Three plants are selected for the studies, namely: Aloe vera (L.), Terminalia chebula Reitz., and T. indica Linn. Estimation of TNF-α in serum (at 1:10 dilution in PBS) was performed using the immunoenzymatic (ELISA) technique. COX inhibitor screening assay kits were used for estimation of COX.Result: All three plant extracts showed a potent significant inhibition of the COX enzyme as compared to the positive control and standard drug when the animal was administered with 400 mg/kg. These studies indicate that the T. indica plant extract showed significant COX inhibition even at low dose. All the extracts were effective anti-inflammatory in nature, however, T. indica extracts at a dose of 400 mg/kg were found to be most potent. It was found to be comparable with that of Indomethacin 10 mg/kg body weight.Conclusion: The anti-inflammatory activity expressed by all the three plants A. vera (L.), T. chebula Reitz., and T. indica L. Among all three plants T. indica (L) was found to be more active against both TNF-α and COX, and it was comparable to standard drug Indomethacin. Need further studies to elucidate the exact secondary metabolite by which these plants express this activity

Global leadership in a university setting

What is global leadership? How can we develop global leadership for a university? This study was conducted using the qualitative approach through in-depth interviews of eight selected top leaders in a selected university. Based on the in-depth interviews, the findings discussed are as follows; Global leadership is related to diversity. Global leaders need to be developed with additional competencies to lead a university and to be able to compete worldwide. Global leadership has to operate in diverse situations. This means that a global leader has to understand different cultures, different ideas and different beliefs. So a global leader has to understand leading in diversity, which requires a different set of competencies. These include attitudes, skills and knowledge. This study is significant because it fills a gap in current knowledge regarding the experience that leaders perceived to be important in understanding and developing global leadership

Analyzing and modeling the influence of workpiece thickness on geometry of slot machining wire EDMs

Wire erosion discharge machining is one of the non-traditional machining processes which use heat energy of spark to remove material from work piece. Process parameters have given the major influence of the cutting performance on wire EDM. Parameters such as pulse on time, peak current, wire diameter and discharge current are well known for their effect surface roughness and recast layer. The present work aimed to investigate the influence of: thickness, current and wire speed on the machining surface. The surface roughness and hardness have been analyzed assessed. It was conclude that surface roughness increase with the increase of thickness and current, and decrease when wire speed increase. Meanwhile, as work piece thickness increase, the surface hardness increase but it decreases when current and wire speed increases

Optical Transmission Plasmonic Color Filter withWider ColorGamut Based on X-Shaped Nanostructure

Extraordinary Optical Transmission Plasmonic Color Filters (EOT-PCFs) with nanostructures have the advantages of consistent color, small size, and excellent color reproduction, making them a suitable replacement for colorant-based filters. Currently, the color gamut created by plasmonic filters is limited to the standard red, green, blue (sRGB) color space, which limits their use in the future. To address this limitation, we propose a surface plasmon resonance (SPR) color filter scheme, which may provide a RGB-wide color gamut while exceeding the sRGB color space. On the surface of the aluminum film, a unique nanopattern structure is etched. The nanohole functions as a coupled grating that matches photon momentum to plasma when exposed to natural light. Metals and surfaces create surface plasmon resonances as light passes through the metal film. The plasmon resonance wavelength can be modified by modifying the structural parameters of the nanopattern to obtain varied transmission spectra. The International Commission on Illumination (CIE 1931) chromaticity diagram can convert the transmission spectrum into color coordinates and convert the spectrum into various colors. The color range and saturation can outperform existing color filters.Funding: This project has received funding from Universidad Carlos III de Madrid and the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant 801538

A study on capabilities of different electrode materials during electrical discharge machining (EDM)

Electrode material in the electro discharge machining (EDM) process plays an important role in terms of material removal rate (MRR), electrode wear rate (EWR) and surface roughness (Ra). The purpose of this research is to investigate the capability of different electrode materials: copper, aluminum, and graphite in EDM of AISI 304 stainless steel as a work piece. The research focuses on three current settings: 2.5A, 4.5A, and 6.5A using kerosene as a dielectric fluid. The experiment was planned and analyzed using the full factorial of experimental design using response surface methodology (RSM). In this research, two outputs have been investigated: MRR and EWR. The results indicated that the responses increased with the increase in current. Finally, the desirability function method has been used to determine the optimum values. The results show that maximum MRR and minimum EWR were achieved using a graphite electrode at current 6.5A. Bahan elektrod dalam proses pengeluaran elektron pada mesin EDM berperanan penting dalam kadar pengeluaran bahan (MRR), kadar penggunaan ekektrod (EWR) dan kekasaran permukaan (Ra). Kajian ini bertujuan bagi menilai keupayaan pelbagai jenis bahan elektrod yang berlainan: tembaga, aluminium, dan grafit dalam EDM pada AISI 304 keluli tahan karat sebagai bahan kajian. Fokus kajian ini pada tiga takat arus: 2.5 A, 4.5 A dan 6.5 A menggunakan kerosin sebagai cecair dielektrik. Eksperimen ini telah dirancang dan diuji menggunakan faktorial penuh pada binaan eksperimen menggunakan kaedah tindak balas pada permukaan (RSM). Dalam kajian ini, dua keputusan telah diuji: MRR dan EWR. Keputusan menunjukkan tindak balas bertambah dengan kenaikan arus. Akhirnya kaedah fungsi keperluan telah digunakan untuk mencari nilai optimum. Keputusan menunjukkan MRR maksimum dan EWR minimum telah dicapai menggunakan elektrod grafit pada arus 6.5 A

A Food Frequency Questionnaire for Hemodialysis Patients in Bangladesh (BDHD-FFQ): Development and Validation

Diet is a recognized risk factor and cornerstone for chronic kidney disease (CKD) management; however, a tool to assess dietary intake among Bangladeshi dialysis patients is scarce. This study aims to validate a prototype Bangladeshi Hemodialysis Food Frequency Questionnaire (BDHD-FFQ) against 3-day dietary recall (3DDR) and corresponding serum biomarkers. Nutrients of interest were energy, macronutrients, potassium, phosphate, iron, sodium and calcium. The BDHD-FFQ, comprising 132 food items, was developed from 606 24-h recalls and had undergone face and content validation. Comprehensive facets of relative validity were ascertained using six statistical tests (correlation coefficient, percent difference, paired t-test, cross-quartiles classification, weighted kappa, and Bland-Altman analysis). Overall, the BDHD-FFQ showed acceptable to good correlations (p 0.05). Cross-quartile classification indicated that <10% of patients were incorrectly classified. Weighted kappa statistics showed agreement with all but iron. Bland-Altman analysis showed positive mean differences were observed for all nutrients when compared to 3DDR, whilst energy, carbohydrates, fat, iron, sodium, and potassium had percentage data points within the limit of agreement (mean ± 1.96 SD), above 95%. In summary, the BDHD-FFQ demonstrated an acceptable relative validity for most of the nutrients as four out of the six statistical tests fulfilled the cut-off standard in assessing dietary intake of CKD patients in Bangladesh